Category: Biomedical & Life Sciences Collection

Recent releases for the Biomedical & Life Sciences Collection of HS Talks. You can search for them in LibrarySearch or directly via the Biomedical & Life Sciences Collection entry on the Online databases and academic journals page in the portal.

In Topical Talks:

The academic basis of primary health care Prof. Trisha Greenhalgh – University of Oxford, UK

In Bioinformatics for Metabolomics:

Analysis of LCMS-based untargeted  metabolomics data 1 Analysis of LCMS-based untargeted  metabolomics data 2 Dr. Pietro Franceschi – Fondazione Edmund Mach, Italy

Metabolomics data analysis in the  context of metabolic networks Dr. Fabien Jourdan – French Agronomic Research  Institute, France

In Cancer Therapies in the Personalized Medicine Era:

Drug metabolizing enzymes in cancer  therapeutics Prof. Bhagwat Prasad – University of Washington, USA

Cancer treatment paradigms Prof. Sharon Marsh – University of Alberta, Canada

In Periodic Reports: Advances in Clinical Interventions and Research Platforms:

Deep Brain Stimulation (DBS)  neuromodulation for Schizophrenia Prof. Judith Gault – University of Colorado, Denver, USA

In Adaptive Clinical Trial:

Patient heterogeneity in dose-finding  trials – part 1: methods for 2 groups Patient heterogeneity in dose-finding  trials – part 2: more than 2 groups Prof. Mark Conaway – University of Virginia, USA

In The Blood-Brain Barrier:

The blood-brain barrier in multiple  sclerosis: A target for treatment? Dr. Elga de Vries – VU Medical Centre, Netherlands

In The Complement System:

Physiopathological implications of  genetic variability in the complement  alternative pathway Prof. Santiago Rodríguez de Córdoba – Centro de  Investigaciones Biológicas, Spain

In Stroke-Prevention:

How to identify which patients with  asymptomatic carotid stenosis could  benefit from endarterectomy or stenting Dr. Kosmas Paraskevas – Athens University Medical School,  Greece

Featured talks from previous releases:

The classical pathway of complement Prof. Mohamed R. Daha – Leiden University Medical Center,  Netherlands

The role of the nurse in supporting health  and well-being for people with learning  (intellectual) disabilities Prof. Ruth Northway – University of South Wales, UK

Parkinson’s at 200 years: an update on  Parkinson’s research in 2017 Prof. Patrick A. Lewis – University of Reading, UK

Recent releases for the Biomedical & Life Sciences Collection of HS Talks. You can search for them in LibrarySearch or directly via the Biomedical & Life Sciences Collection entry on the Online databases and academic journals page in the portal.

In Mitochondrial Biogenesis:

Exercise-induced mitochondrial biogenesis  in muscle 1 Exercise-induced mitochondrial biogenesis  in muscle 2 Prof. David Hood – York University, Canada

In Mitochondria in Health and Disease:

Human mitochondrial tRNAs:  post-transcriptional modifications and  diseases Prof. Tsutomu Suzuki – The University of Tokyo, Japan

Suppressing mosquito disease vectors  via manipulating fertility, sex and  male-courtship drive Prof. Craig Montell – University of California, Santa Barbara,  USA

In The Complement System:

Complement deficiencies in humans Prof. Francesco Tedesco – Istituto Auxologico Italiano, Italy

In Bioinformatics for Metabolomics:

Metabolomics: importance of experimental  design to data acquisition 1 Metabolomics: importance of experimental  design to data acquisition 2 Dr. Oscar Yanes – Universitat Rovira i Virgili, Spain

Data sharing and data standards for  metabolomics: where are we now? Dr. Reza Salek – The European Bioinformatics Institute, UK

In Design and Analysis of Randomized Clinical Trials:

Design and conduct of non-inferiority  trials Prof. Valerie Durkalski-Mauldin – Medical University of South  Carolina, USA

In Adaptive Clinical Trial:

Implementation of adaptive methods in  early phase clinical trials Prof. Gina Petroni – University of Virginia, USA

In Periodic Reports: Advances in Clinical Interventions and Research Platforms:

Impact of the HPV vaccine programme –  a changing landscape Dr. Kevin Pollock – Health Protection Scotland, UK

In Topical Talks:

Introduction to patents in the pharmaceutical  industry Dr. Jonathan D.M. Atkinson – HGF Limited, UK

Autism specific pedagogic intervention (ASP) Dr. Abdulbaghi Ahmad – Uppsala University, Sweden

Short interviews:

Opposition to vaccination: a transatlantic  discussion Prof. Jonathan Temte – University of Wisconsin, USA

Elective caesarean sections from an  evolutionary perspective Prof. Wenda Trevathan – New Mexico State University, USA

Translational research in amyotrophic lateral  sclerosis (ALS) Prof. Aaron D. Gitler – Stanford University School of Medicine, USA

Featured talks from previous releases:

Amino acid conjugation: mechanism and  enzymology Dr. Kathleen Knights – Flinders University, Australia

DNA damage, mutations and aging 1 Prof. Jan Vijg – Albert Einstein College of Medicine, USA

History of vaccines Prof. Stanley Plotkin – University of Pennsylvania and Sanofi Pasteur,  USA

Recent releases for the Biomedical & Life Sciences Collection of HS Talks. You can search for them in LibrarySearch or directly via the Biomedical & Life Sciences Collection entry on the Online databases and academic journals page in the portal.

In Gene-drives and Active Genetics:

The dawn of active genetics Prof. Ethan Bier – University of California, San Diego, USA

Public response to a proposed field trial of   genetically engineered mosquitoes in the  United States Prof. Cinnamon Bloss – University of California, San Diego, USA

Population modification of malaria vector  mosquitoes Dr. Anthony A. James – University of California, Irvine, USA

Ecological considerations for gene drive  systems Prof. Gregory C. Lanzaro – University of California, Davis, USA

Guidance for responsible testing and  implementation of gene-drive systems Prof. Stephanie James – Foundation for the National Institutes of  Health, USA

Gene drive behavior when pest populations  have age, mating and spatial structure Prof. Fred Gould – North Carolina State University, USA Prof. Alun Lloyd – North Carolina State University, USA

In Periodic Reports: Advances in Clinical Interventions and Research Platforms:

An update on the multiple faces of celiac  disease Prof. Aaron Lerner – Technion-Israel Institute of Technology, Israel

Complement and organ transplantation Prof. Steven Sacks – King’s College London, UK

In Viruses and Viral Diseases:

Antiviral drugs (non-HIV) Prof. Megan Shaw – Mount Sinai, USA

In Molecular Chaperones:

The roles of molecular chaperones in  bacterial infection Prof. Tomoko Yamamoto – Chiba University, Japan

In Bioinformatics for Metabolomics:

Metabolomics flux on the genome scale Prof. Marta Cascante – University of Barcelona, Spain Dr. Igor Marín de Mas – University of Barcelona, Spain

In Using Bioinformatics in the Exploration of Genetic Diversity:

The predominant clonal evolution (PCE)  concept of microbial pathogens and its  practical usefulness Dr. Michel Tibayrenc – Institut de Recherche pour le Developpement,  France

Recent releases for the Biomedical & Life Sciences Collection of HS Talks. You can search for them in LibrarySearch or directly via the Biomedical & Life Sciences Collection entry on the Online databases and academic journals page in the portal.

In Mitochondria in Health and Disease:

Mitochondrial transporters and disease –  function and mechanism Dr. Edmund R.S. Kunji – University of Cambridge, UK

Mitochondrial transporters and disease –  structure and regulation Dr. Edmund R.S. Kunji – University of Cambridge, UK

Biogenesis of cellular iron-sulfur proteins:  structure, function, and assembly in  mitochondria Prof. Roland Lill – Philipps-Universität Marburg, Germany

In Periodic Reports: Advances in Clinical Interventions and Research Platforms:

Latest development in therapy-related  autophagy research Dr. Vignir Helgason – University of Glasgow, UK

In Bioinformatics for Metabolomics:

Metabolomics flux introduction Prof. Marta Cascante – University of Barcelona, Spain Dr. Igor Marín de Mas – University of Barcelona, Spain

In The Blood-Brain Barrier:

Tanycytes allow a tight BBB in the  median eminence Prof. Esteban Rodriguez – Austral University, Chile Dr. Juan Luis Blazquez – University of Salamanca, Spain Dr. Montserrat Guerra – Austral University, Chile

In Drug Metabolizing Enzymes:

Amino acid conjugation: mechanism and  enzymology Dr. Kathleen Knights – Flinders University, Australia

In Topical Talks:

An approach to giant cell arteritis (GCA) Dr. Alison Clifford – University of Alberta, Canada

Global variation in human tooth crown and  root morphology – anthropological and  forensic applications – 1 Prof. G. Richard Scott – University of Nevada, USA

Global variation in human tooth crown and  root morphology – anthropological and  forensic applications – 2 Prof. G. Richard Scott – University of Nevada, USA

Subarachnoid hemorrhage – a Bayesian  approach to a neurological black swan Dr. John Bedolla – University of Texas Dell Medical School,  USA

In From DNA to Proteins:

Elongation of protein synthesis: structural  basis of the process of decoding Prof. Marina Rodnina – Max Planck Institute for  Biophysical Chemistry, Germany

HS Talks launch a new series of short audio interviews with scientists and clinicians, discussing their views on current challenges and future directions in their fields. This month’s release includes the following:

Current directions in the prevention and  treatment of Alzheimer’s disease Prof. John Hardy – Institute of Neurology, University College  London, UK

PANDAS: a potential link between group A  streptococcal infections and neurological  disorders Prof. P. Patrick Cleary – University of Minnesota, USA

Towards developing a universal influenza  vaccine Prof. Peter Palese – Mount Sinai School of Medicine, USA

Rheumatic diseases and musculoskeletal  pain Prof. Anisur Rahman – University College London, UK

Antiphospholipid syndrome and Lupus Prof. Graham Hughes – London Lupus Centre, UK

Prescribing medications to children – a GP’s  view Dr. Amanda Simmons – General practitioner, UK

Recent releases for the Biomedical & Life Sciences Collection of HS Talks. You can search for them in LibrarySearch or directly via the Biomedical & Life Sciences Collection entry on the Online databases and academic journals page in the portal.

Pulmonary drug delivery Prof. Anthony J. Hickey – RTI  International, USA

Adaptation in likelihood trials Prof. Jeffrey Blume – Brown  University, USA

Priming of T cell responses 1 Priming of T cell responses 2 Prof. Victor Appay – INSERM, France Dr. Francesco Nicoli – Universities of Ferrara and Padua, Italy

The world of lupus Prof. Graham Hughes – London Lupus Centre, UK

Systemic lupus erythematosus: diagnosis and  management Dr. Sara K. Tedeschi – Harvard Medical School, USA

Germinal centre lymphomas: advances in diagnostic  and therapeutic intervention Dr. Koorosh Korfi – Barts Cancer Institute, UK Prof. Jude Fitzgibbon – University of London, UK

Expanding roles of RNA-binding proteins  in neurodegenerative diseases Prof. Aaron D. Gitler – Stanford University  School of Medicine, USA

C3 glomerulopathy Prof. Matthew Pickering – Imperial College London, UK

Data fusion: examples in fusing metabolomics  and transcriptomics data Dr. Johan A. Westerhuis – University of Amsterdam,  Netherlands

Brain anatomy and functional differences in  developmental stuttering Prof. Soo-Eun Chang – University of Michigan, USA

The role of the nurse in supporting health and  well-being for people with learning (intellectual) disabilities Prof. Ruth Northway – University of South Wales, UK

Recent releases for the Biomedical & Life Sciences Collection of HS Talks. You can search for them in LibrarySearch or directly via the Biomedical & Life Sciences Collection entry on the Online databases and academic journals page in the portal.

The Complement System:

The evolution of complement and the alternative pathway Prof. Sir Peter Lachmann – University of Cambridge, UK

Complement diagnostics Dr. Ashley Frazer-Abel – University of Colorado, USA

Complement in PNH and other hemolytic anaemias 1 Complement in PNH and other hemolytic anaemias 2 Complement in PNH and other hemolytic anaemias 3 Prof. Lucio Luzzatto – Muhimbili University of Health and Applied  Sciences, Tanzania

Statistical Genetics:

Imputation in genome-wide association analysis Prof. Jonathan Marchini – University of Oxford, UK

Protein Epidemiology:

GM2 gangliosidosis future treatments 1 GM2 gangliosidosis future treatments 2 Prof. Brian Mark – University of Mantoba, Canada

Evolution and Medicine:

Hard tissue biology in human health and evolution:  enamel biology + Hard tissue biology in human health and evolution:  bone biology +  Prof. Timothy Bromage – New York University, USA

Oral & Maxillofacial Medicine:

Soreness and ulcers 5: biology, diagnosis and management  of cancer regimen 1 Soreness and ulcers 5: biology, diagnosis and management  of cancer regimen 2 Prof. Stephen T. Sonis – Brigham and Women’s Hospital and the  Dana-Farber Cancer Institute, USA

Trismus Prof. Tara Renton – Kings College London, UK

Recent releases for the Biomedical & Life Sciences Collection of HS Talks. You can search for them in LibrarySearch or directly via the Biomedical & Life Sciences Collection entry on the Online databases and academic journals page in the portal.

Ecology:

Decision ecology: what natural decision-making tells us  about the structure of the brain and neural systems Prof. David W. Stephens – University of Minnesota, USA

Macroecology Dr. Natalie Cooper – Natural History Museum, London, UK

Why is the world green? Top-down and  bottom-up controls on ecosystems Prof. Jonathan Shurin – University of California-San Diego,  USA

Topical Talks:

The management of systemic lupus  erythematosus Prof. Anisur Rahman – University College London, UK

Periodic Reports: Advances in Clinical Interventions and Research Platforms:

Recent advances in diagnosis and interventions  in ophthalmology Dr. Rebecca Kaye – University of Southampton, UK Prof. Andrew Lotery – University of Southampton, UK

Aging:

Rejuvenation biotechnology: postponing III – health  via comprehensive damage repair Dr. Aubrey de Grey – SENS Foundation, USA

Macular Degeneration:

Epigenetics in age-related macular degeneration Prof. Andrew Lotery – University of Southampton, UK

 Adaptive Clinical Trial Design:

Frequentist approaches: sample size in  adaptive clinical designs Prof. Tatsuki Koyama – Vanderbilt University, USA

RNA Interference:

RNA interference functions and mechanisms in animals Prof. Richard Carthew – Northwestern University, USA

Speech Dysfluency:

Atypical disfluency: understanding and treating  word-final (end-word) repetition Prof. Vivian Sisskin – University of Maryland, USA

Recent releases for the Biomedical & Life Sciences Collection of HS Talks. You can search for them in LibrarySearch or directly via the Biomedical & Life Sciences Collection entry on the Online databases and academic journals page in the portal.

Bioinformatics for Metabolomics:

NMR workflow from data processing to metabolite  identification Dr. Gwénaëlle Le Gall – Quadram Institute, UK

Univariate statistics and metabolomics Dr. Ron Wehrens – Wageningen University & Research,  Netherlands

Multivariate statistics and metabolomics Dr. Ron Wehrens – Wageningen University & Research,  Netherlands

FAIR data in metabolomics Prof. Dr. Christoph Steinbeck – Friedrich-Schiller-University,  Germany

MassBank and RMassBank Dr. Emma L. Schymanski – University of Luxembourg,  Luxembourg

Topical Talks:

Avoiding missed diagnosis of mild traumatic  brain injury Prof. John Bedolla – University of Texas Dell Medical School,  USA

The Salford lung study in COPD Dr. Dave Leather – GSK Global Respiratory Franchise, UK

The Complement System:

Subversion of complement by bacteria Prof. Seppo Meri – University of Helsinki, Finland

Alzheimer’s Disease/ Periodic Reports: Advances in 
Clinical Interventions and Research Platforms:

Alzheimer’s disease: where are we up to? + Prof. John Hardy – Institute of Neurology,  University College London, UK

Cancer Therapies in the Personalized Medicine Era:

Clinical research and care in the era of ‘N-of-1’ precision cancer medicine Prof. Maurie Markman – Cancer Treatment Centers of America,  USA

Adaptive Clinical Trial Design:

Adaptive clinical trial design: randomization Prof. Hao Liu – Indiana University School of Medicine,  USA

Speech Dysfluency:

Bridging our mandates: evidence-based practice (EBP)  and patient-centered care (PCC) 1 Bridging our mandates: evidence-based practice (EBP)  and patient-centered care (PCC) 2 Prof. Nan Bernstein Ratner – University of Maryland, USA